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Comparison of intratracheal oxygen concentration and safe apnoea time under different apnoeic oxygenation techniques: a single-center randomized, controlled study

Comparison of intratracheal oxygen concentration and safe apnoea time under different apnoeic oxygenation techniques: a single-center randomized, controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067642
Enrollment
Unknown
Registered
2023-01-16
Start date
2023-01-16
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

apnoeic oxygenation techniques

Interventions

low-flow nasal oxygenation2:Nasal oxygenation, oxygen flow 2L/min
low-flow nasal oxygenation5:Nasal oxygenation, oxygen flow 5L/min
low-flow nasal oxygenation10:Nasal oxygenation, oxygen flow 10L/min
the nasopharyngeal airway group:Modified nasopharynx airway oxygenation, oxygen flow 10L/min

Sponsors

Department of anaesthesia, Obstetrics and Gynecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Female patients aged 18-60 years with American Society of Anesthesiologists (ASA) grades I-II undergoing elective laparoscopic gynaecological surgery under general anaesthesia were enrolled in this study.

Exclusion criteria

Exclusion criteria: The exclusion criteria included the following: anatomical abnormalities or a surgical history of the face, nose, or upper airway; nasal obstruction or difficulty placing the nasopharyngeal airway; difficult airway; a New York Heart Association (NYHA) cardiac function classification > 2; smoking; chronic respiratory diseases; uncontrolled hypertension; elevated intracranial pressure; SpO2 below 97% after pure oxygen inhalation for 3 minutes; incorporation with facemask ventilation; a body mass index (BMI) >= 30 kg/m^2; pregnancy; severe gastroesophageal reflux; neuromuscular disease; and refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
tracheal oxygen fraction, FtO2;periglottic oxygen fraction, FgO2;the safe apnoea time;

Countries

China

Contacts

Public ContactWeilian Geng

Department of anaesthesia, Obstetrics and Gynecology Hospital of Fudan University

irisgenggeng@126.com+86 137 6427 8766

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026