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Clinical study of migraine patients with patent foramen ovale based on resting-state functional magnetic resonance imaging

Clinical study of migraine patients with patent foramen ovale based on resting-state functional magnetic resonance imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067636
Enrollment
Unknown
Registered
2023-01-15
Start date
2022-12-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

migraine

Interventions

Migraine with patent foramen ovale:None
Migraine without patent foramen ovale:None
Health control:None

Sponsors

Shanghai Six People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of migraine of the third edition of the International Classification of Headache Diseases (ICHD-3 ß) . (2) 14 <= age <= 70 years old (3) There was no migraine attack within 3 days before the scan, on the scan day and 1 day after the scan. (4) Auxiliary inspection results are complete. (5) Informed consent of patients.

Exclusion criteria

Exclusion criteria: (1) Other types of primary headache, excluding secondary headache. (2) Previous mental diseases, such as anxiety, depression, dementia, etc. (3) Previous cerebral infarction, cerebral hemorrhage or other intracranial structural lesions; (4) Have a history of alcohol and drug addiction, and a history of drug prevention within one year. (5) Migraine attack on the same day or within 24 hours after scanning (6) Unable to cooperate with MRI and transesophageal echocardiography.

Design outcomes

Primary

MeasureTime frame
data of brain resting-state functional magnetic resonance imaging;Classification of patent foramen ovale;headache days;Headache frequency;degree of pain;

Secondary

MeasureTime frame
Headache Impact Test Questionnaire (HIT-6) score;

Countries

China

Contacts

Public ContactYang Jiajun

Shanghai Six People's Hospital

sd_yangjj@sumhs.edu.cn+86 158 2185 3149

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026