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Expression and regulation of related differential proteins in follicular fluid and granulosa cells of PCOS patients

Expression and regulation of related differential proteins in follicular fluid and granulosa cells of PCOS patients

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067599
Enrollment
Unknown
Registered
2023-01-13
Start date
2022-01-08
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrome

Interventions

Polycystic ovary syndrome disease group:No intervention
Non-polycystic ovarian syndrome group:No intervention

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: (1) Female, aged 18-35 years, with normal ovarian reserve, AMH>1.3, AFC>=10, bFSH<10mIU/ml, patients with polycystic ovary and non-polycystic ovary who underwent in vitro fertilization-embryo transfer in the reproductive center Syndromic patients; (2) PCOS patients: rare and / or anovulatory; polycystic ovarian changes on ultrasound; hyperandrogenism and/or hyperandrogen signs, if two of the above three are met, the diagnosis can be made.

Exclusion criteria

Exclusion criteria: Cardiovascular disease, diabetes, congenital adrenal hyperplasia, androgen-secreting tumors, hyperprolactinemia and other diseases that lead to abnormal ovulation or hyperandrogenism were excluded.

Design outcomes

Primary

MeasureTime frame
Protoestrogens;Hydroxylated estrogen;Methoxyestrogen;Androgen;

Countries

China

Contacts

Public ContactBei Zhang

Xuzhou Central Hospital

bettyzhang10@163.com18952171130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026