Perioperative analgesia for gallbladder surgery
Conditions
Interventions
Group NS:Physiological saline
Group LS:After giving 0.5mg/kg of esketamine intravenously before cutting the skin, 2ug/kg-min continuous pumping was given respectively.
Group HS:After giving 0.5mg/kg of esketamine intravenously before cutting the skin, 4ug/kg-min continuous pumping was given respectively.
Sponsors
Hefei First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria (1): age 18 to 65 years; (2) ASA classification grade I to II; (3) confirmed diagnosis of gallbladder stones, polyps or chronic cholecystitis; (4) ability to communicate normally; (5) informed consent and signed informed consent form by patients and family members.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) patients with mental disorders; (2) allergic to this drug; (3) those with other infections and biliary system diseases; (4) those with coexisting abnormal liver, kidney and lung functions and hematological diseases; (5) those with contraindications to surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood stress index;Blood inflammatory response;Intraoperative and 24-hour postoperative sufentanil dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure; | — |
Countries
China
Contacts
Public ContactHengYang
Hefei First People's Hospital South
Outcome results
None listed