A randomized controlled clinical study of articulation function after platysma skin flap repair and banded muscle repair for unilateral T2-3 glottic laryngeal carcinoma

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067582

Enrollment

Unknown

Registered

2023-01-12

Start date

2023-01-15

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glottic laryngeal carcinoma

Interventions

Platysma skin flap group :Vertical partial laryngectomy+platysma skin flap repair

Band musculocutaneous flap group:Vertical partial laryngectomy+Band musculocutaneousflap repair

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age:18~75. 2.Patients had not received surgery or chemoradiotherapy before the clinical study began. 3.Patients with pathological diagnosis of laryngeal squamous cell carcinoma (including various differentiation) 4.Patient was diagnosed with unilateral glottic laryngeal carcinoma with clinical stage T2N0M0 or T3N0M0(AJCC TNM stage in 2002) 5.Patient's KPS>=70 6.Patient has signed an informed consent

Exclusion criteria

Exclusion criteria: 1.Patient was suffering from other serious infectious diseases such as tuberculosis and leprosy. 2.Patients suffering from critical organs such as heart, brain, lung function severe abnormalities. 3.Patients suffering from severe blood coagulation dysfunction.

Design outcomes

Primary

Measure	Time frame
VHI-10 questionnaire scores;	—

Secondary

Measure	Time frame
GRBAS questionnaire scores;Aerodynamics test score;3-year recurrence free survival rate;	—

Countries

China

Contacts

Public ContactQian Cai

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

caiqian2@mail.sysu.edu.cn13710709975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026