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The study of feasibility of adaptive radiotherapy based on 18F-FDG PET imaging feedback/tumor dose response assessment in nasopharyngeal carcinoma patients

The study of feasibility of adaptive radiotherapy based on 18F-FDG PET imaging feedback/tumor dose response assessment in nasopharyngeal carcinoma patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067580
Enrollment
Unknown
Registered
2023-01-12
Start date
2023-01-03
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharygeal Carcinoma

Interventions

PET/MRI scan group:N/A

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Participants must have histologically or cytologically confirmednasopharygeal carcinoma 2. Clinical stage must be I-IVA (AJCC 8th ed.) 3.Age>=18 4.Participants must not have received any anti-tumor treatment before 5.ECOG performance status =1,500/mcL, platelets>=100,000/mcL,hemoglobin>=9 g/dL 7.AST(SGOT)/ALT(SGPT) =60 mL/min using the Cockcroft-Gault equation 9.Ability to understand and the willingness to sign a written informed consent document

Exclusion criteria

Exclusion criteria: 1.Age<18 2.Uncontrolled ongoing or active infection or trauma 3.Active or treated tuberculosis diagnosed within 1 year, or participants who were diagnosed with tuberculosis over 1 year but didnt received standard treatments. 4.Participants must not have known history or current diagnosis of malignancy, excluding carcinoma in situ, well-treated non-melanoma skin cancer and papillary thyroid carcinoma. 5.Known HIV-positive participants are ineligible 6.Uncontrolled illness including symptomatic congestive heart failure, unstable angina pectocariris, cardiac arrhythmia, myocardial infarction, pulmonary interstitial fibrosis, infection or psychiatric illness/social situations that would limit compliance with study requirements 7.Intolerant or allergic to 18F-FDG contrast

Design outcomes

Primary

MeasureTime frame
Voxel signal intensity of PET/MRI;

Countries

China

Contacts

Public ContactShu Zhang

West China Hospital, Sichuan Unviersity

echo13032619@163.com13981906698

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026