Dopamine Regulation Mechanism of Circadian Rhythm Disorders on Working Memory of Pilots

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067541

Enrollment

Unknown

Registered

2023-01-11

Start date

2023-01-11

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circadian Rhythm Disorders

Interventions

Healthy control group:Sleep intervention

Pilot group:N/A

Eligibility

Sex/Gender

Male

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: (1) Male, 20 years old - 55 years old (2) The pilots can ensure normal attandence during the test. The healthy subjects need to be non-shift working group, which means they can not work before 8am or late than 9pm.

Exclusion criteria

Exclusion criteria: (1) The volunteers who have took sedative hypnotics or other antidepressant, antianxiety, antipsychotic drugs in the past three month will be excluded. (2) The volunteers who have other sleep disorders (such as Restless legs Syndrome, etc.) will be excluded. (3) The volunteers with history of mental disease or endocrine disease will be excluded. (4) The volunteers with history of the other serious diseases will be excluded.

Design outcomes

Primary

Measure	Time frame
Working memory;neuroimaging;Dopamine;Sleep Quality;cortisol;melatonin;catecholamine;Dopamine receptor;	—

Secondary

Measure	Time frame
Depression;Anxiety;Height;Weight;	—

Countries

China

Contacts

Public ContactSun Yuanfeng

West China Hospital, Sichuan University

yuanfengsunscu@126.com17702834255

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026