Ankylosing spondylitis
Conditions
Interventions
Treatment group:Tongdu Shujin decoction
Control group :Celecoxib capsules and thalidomide tablets
Sponsors
The First Affiliated Hospital of Henan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) Western medical diagnostic criteria for AS; (2) TCM dialectic is cold-dampness obstruction type; (3) 18-40 years old, male or female; (4) Women of childbearing age proved to be not pregnant after testing, and there was no pregnancy plan during the entire trial period; (5) Not taking any AS treatment drugs in the 1 month period before receiving treatment; (6) Voluntarily participate in this trial and agree to enter the clinical study, sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) patients with other rheumatic immune system diseases; (2) Those with serious diseases such as heart, brain, lung, liver, kidney, tumor, infection or hematopoietic system; (3) Patients who are taking other Chinese medicine treatment for certain diseases; (4) Lactating or pregnant women; (5) Those who are allergic to the drugs in this test; (6) Patients with mental disorders who cannot communicate effectively; (7) Those who are active peptic ulcer, bleeding or sulfa allergy; (8) Patients with severe heart failure; (9) Patients with perioperative pain during coronary artery bypass graft.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale;Bath Ankylosing Spondylitis Disease Activity Index;Bath ANKYLOSING Spondylitis Functional Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythrocyte sedimentation rate;C-reactive protein;Spinal range of motion ( including finger-ground distance, occipital tubercle-wall distance, Schober test ); | — |
Countries
China
Contacts
Public ContactZihua Wang
The First Affiliated Hospital of Henan University of Chinese Medicine
Outcome results
None listed