Emergence agitation in Pediatric Tonsillectomy and Adenoidectomy
Conditions
Interventions
Dexmedetomidine(group D):Dexmedetomidine was infused by 0.3µg/kg in 10min
Dexmedetomidine and esketamine 0.1mg/kg(group DE1):Dexmedetomidine was infused by 0.3µg/kg in 10min and esketamin 0.1mg/kg iv
Dexmedetomidine and esketamine 0.1mg/kg(group DE2):Dexmedetomidine was infused by 0.3µg/kg in 10min and esketamin 0.2mg/kg iv
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. ASA I-II; 2. 3-7 years old; 3. Selective tonsillectomy and adenoidectomy operation under general anesthesia in children
Exclusion criteria
Exclusion criteria: 1. The guardian of the child refuses the test; 2. Suffering from serious chronic diseases such as heart, liver and kidney; 3. There were obvious abnormalities in preoperative examination (electrocardiogram, plain chest film); 4. Patients with obstructive sleep apnea syndrome (OSAS), asthma, upper airway abnormalities, and a history of respiratory infection in the last 2 weeks; 5. Developmental retardation or BMI > 30kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of emergence agitation in Pediatric Tonsillectomy and Adenoidectomy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The best drug combination with fewer adverse reactions; | — |
Countries
China
Contacts
Public ContactKai Zeng
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed