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Establishment of a rapid detection method for microorganisms in the lower genital tract using MALDI-TOF MS and its clinical application in infertility

Establishment of a rapid detection method for microorganisms in the lower genital tract using MALDI-TOF MS and its clinical application in infertility

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067518
Enrollment
Unknown
Registered
2023-01-10
Start date
2023-02-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

control group:none

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Case group 1) Female aged 18-40 2) Regular menstrual cycle 2) Conform to the clinical diagnosis of infertility 3) No sexual life 3 days before the examination control group 1) Female aged 18-40 2) Regular menstrual cycle 3) Patients who did pre-pregnancy consultation in our hospital, pregnant at the time of 3-month follow-up 4) No sexual life 3 days before the examination

Exclusion criteria

Exclusion criteria: Case group: 1) Infertility due to malformation of reproductive tract 2) Infertility caused by endocrine factors such as polycystic ovary syndrome, premature ovarian failure and severe hyperthyroidism 3) Infertility due to male factors 4) Patients with malignant tumors 5) Patients with autoimmune diseases 6) Patients with severe heart, kidney and other basic diseases 7) Patients who consumed antibiotics 3 days before the examination 8) Have the habit of smoking and drinking Control group: 1) Pregnancy by various assisted reproductive means 2) Patients with malignant tumors 3) Patients with autoimmune diseases 4) Patients with severe heart, kidney and other basic diseases 5) Patients who consumed antibiotics 3 days before the examination 6) Have the habit of smoking and drinking

Design outcomes

Primary

MeasureTime frame
Lower genital tract pathogen;

Secondary

MeasureTime frame
Lower genital tract Community State Types;

Countries

China

Contacts

Public ContactZhiying Yu

Shenzhen Second People's Hospital

lizheyzy@163.com+86 13923801588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026