Heart Disease
Conditions
Interventions
PSB group:one single nerve block immediately after surgery, and then continuous parasternal nerve block,administer intravenous opioid analgesics as needed
control group:one single nerve block immediately after surgery, and then Patient controlled intravenous analgesia
Sponsors
The First Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 years and over; 2. Preoperative echocardiography: M-mode ultrasound Teichholz method to measure left ventricular ejection fraction ( Left Ventricular Ejection Fraction (LVEF) >= 50%; 3. Elective thoracotomy under heart surgery; 4. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Need IABP, ECMO and other devices to assist circulation before or after operation; 2. Contraindication of nerve block; 3. History of open heart surgery; 4. Opioid dependence; 5. Impairment of cognitive function; 6. History of chronic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total amount of opioids in the 48 hours after surgery (converted to morphine equivalent); | — |
Secondary
| Measure | Time frame |
|---|---|
| parasternal pain numeric rating scale;parasternal pain threshold;Nausea and Vomiting incidence;Postoperative mechanical ventilation time;Length of ICU stay;Time to breathing exercise after surgery;Time to get out of bed after surgery;Satisfaction with analgesia;Incidence of moderate to severe pain;Response time to instructions;Start intravenous opioids to remedy the analgesic duration;Intravenous opioid remedial dose (converted to morphine equivalent);Number of intravenous opioid remedies;rapid shallow breathing index;postoperation plasma ropivacaine concentration; | — |
Countries
China
Contacts
Public ContactChen Yu
The First Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed