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The clinical study of evaluation of nutritional status and sarcopenia before transjugular intrahepatic portosystemic shunts and prediction of post-operative adverse events in liver cirrhosis

The clinical study of evaluation of nutritional status and sarcopenia before transjugular intrahepatic portosystemic shunts and prediction of post-operative adverse events in liver cirrhosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067513
Enrollment
Unknown
Registered
2023-01-10
Start date
2023-02-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cirrhosis

Interventions

Decompensated cirrhosis group:N/A

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 to 75 years; 2. Patients with decompensated liver cirrhosis; 3. Patients with refractory hydrothorax/ascites or esophageal and gastric varices bleeding, who are going to receive selective TIPS.

Exclusion criteria

Exclusion criteria: 1. Previous TIPS or surgical shunt; 2. Uncontrolled or stabilized for less than one week liver cirrhosis complications such as gastrointestinal bleeding, spontaneous peritonitis, hepatorenal syndrome and hepetopulmonary syndrome; 3. Dysfunction of organs including heart, lung, kidney and brain; 4. Uncorrectable blindness, amblyopia or ametropia; 5. Extremely low cultural degree, unable to read or write simple words; 6. From high altitude area (higher than 2500 meters above the sea level); 7. Pregnant and lactating women; 8. Child-Pugh score is greater than 12, aminopherase exceeds five times higher than the normal upper limit; 9. Liver cancer and other malignant tumors beyond Milan criteria.

Design outcomes

Primary

MeasureTime frame
Adverse events such as hepatic encephalopathy, infections, liver failure and so on.;Blood biochemical indices.;Sarcopenia/malnutrition assessment scale.;

Countries

China

Contacts

Public ContactHao Wu

West China Hospital, Sichuan University

594264513@qq.com18980601287

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026