Efficacy of an internet-based cognitive behavioral intervention for psychological distress for people with Hepatitis B Virus: A pilot randomized controlled trial

Mental health improvement for patients with infectious disease from the perspective of resilience

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067511

Enrollment

Unknown

Registered

2023-01-10

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, anxiety, Hepatitis B Virus Infection

Interventions

Experimental:Cognitive-behavioral intervention

Control:4-week waitlist

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 or older; 2. Have a positive Hepatitis B surface antigen test result 3. DASS-21 depressive symptom score >10, anxiety symptoms score > 8, or stress levels score > 15; 4. Possess a smartphone; 5. Provided informed consent

Exclusion criteria

Exclusion criteria: 1. Complicating other chronic hepatitis such as Hepatitis C, autoimmune hepatitis, alcoholic hepatitis and fatty liver 2. Have other choric diseases. 3. Are currently receiving psychotherapy or psychological counselling. 4. Participating in other clinical trials. 5. Had been diagnosed with psychiatric or psychological disorders. 6. Had suicidal ideation for the past six months.

Design outcomes

Primary

Measure	Time frame
Depression Anxiety Stress Scale-21 (DASS-21);	—

Secondary

Measure	Time frame
Adherence to anti-viral treatment;Hepatitis B virus DNA quantification;Satisfaction to intervention;Adherence to intervention;	—

Countries

China

Contacts

Public ContactZhou GuangYu

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behaviour and Mental Health, Peking University

gyzhou@pku.edu.cn(010) 62751820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026