cholecystolithiasis combined with small-diameter choledocholithiasis
Conditions
Interventions
Observation group:laparoscopic cholecystectomy(LC) +laparoscopic common bile duct exploration(LCBDE)+primary duct closure (PDC)+ endoscopic nasobiliary drainage(ENBD)
control group:laparoscopic cholecystectomy(LC)+ endoscopic retrograde cholangioancreatography(ERCP)/endoscopic sphincterotomy(EST) + endoscopic nasobiliary drainage(ENBD)
Sponsors
The First Hospital of Changsha
Eligibility
Sex/Gender
All
Age
21 Years to 60 Years
Inclusion criteria
Inclusion criteria: ? Patients were diagnosed by preoperative symptoms and imaging examination (abdominal B ultrasound, CT, MRCP). ? The diameter of common bile duct =0.8cm. ? Age of 18-60 years old, both sexes. ? no biliary stricture, malformation or tumor. ? no hepatolithiasis, cholangitis, acute pancreatitis, Mirrizzi syndrome. ? patients undergoing elective surgery. ? Informed consent was obtained and signed.
Exclusion criteria
Exclusion criteria: ? Severe complications or rapid progression of the disease requiring emergency surgery. ? abnormal heart, brain, lung, kidney function, poor general condition, can not tolerate surgery. ? poor function or stenosis of duodenal papilla. ?history of biliary tract surgery or abdominal surgery. ? Unable to follow up or lost follow-up. ? patients with mental illness. ? Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total bilirubin;direct bilirubin;alanine aminotransferase;aspartate aminotransferase;serum amylase;operation success rate;stone clearance rate;operation time;intraoperative blood loss;postoperative gastrointestinal function recovery time;postoperative hospital stay;postoperative complications;hospitalization cost; | — |
Countries
China
Contacts
Public ContactJiaojiao Xu
The First Hospital of Changsha
Outcome results
None listed