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Application of Sulodexide in the Treatment of Refractory Posner-Schlossman Syndrome:A self-controlled Study

Application of Sulodexide in the Treatment of Refractory Posner-Schlossman Syndrome:A self-controlled Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067473
Enrollment
Unknown
Registered
2023-01-09
Start date
2023-01-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posner-Schlossman Syndrome

Interventions

Research Group:sulodexide

Sponsors

The Eye of Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with Posner-Schlossman Syndrome cannot control intraocular pressure and anterior chamber inflammation after using hormones (including some antiviral drugs) for 2 weeks, or whose intraocular pressure and inflammation rebound once hormone is stopped; Older than 18

Exclusion criteria

Exclusion criteria: 1. Allergies to sulodexide, heparin or heparin like drugs; 2. Patients with coagulation dysfunction or bleeding tendency; 3. Patients diagnosed with other eye diseases such as uveitis, keratopathy and fundus diseases , except for ametropia, cataract and glaucoma; 4. Patients with diseases requiring long-term sex hormone treatment and glucocorticoid treatment, such as primary aldosteronism, polycystic ovary syndrome and lupus erythematosus; patients taking spironolactone orally to control blood pressure; pregnant women and premenopausal women; 5. Patients who also participate in clinical trials of other drugs.

Design outcomes

Primary

MeasureTime frame
intraocular pressure;

Secondary

MeasureTime frame
anterior chamber inflammation;

Countries

China

Contacts

Public ContactYuanbo Liang

The Eye of Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University

yuanboliang@126.com+86 18257748686

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026