advanced cervical cancer
Conditions
Interventions
Observation group:None
Sponsors
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. FIGO IIA -- IV patients initially treated for cervical cancer; 2. Patient =18 years old; 3. No previous tumor history; 4. Tumor tissue, paracancer tissue/blood control can be obtained; 5. Complete clinical data of patients; 6. Laboratory examination: WBC=3.0×109/L, NEU=2.0×109/L, PLT=80×109/L, serum bilirubin = 2 times of the high limit of normal value, transaminase = 2 times of the high limit of normal value, BUN, Cr= normal value; 7. Volunteer to participate in the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Participating in clinical trials of other drugs; 2. Abnormal liver and kidney function (the index is more than 3 times higher than the normal value); 3. Respiratory depression, airway obstruction or tissue hypoxia; 4. Heart disease (heart function of grade ? and above); Blood system diseases; 5. 6. Asexual life history; 7. Have received neoadjuvant chemoradiotherapy and surgical treatment for cervical cancer; 8. Those who cannot undergo cervical examination for genital tract malformations; 9. Patients who cannot tolerate chemotherapy; 10. Previous history of other oncology diseases, immune diseases, and other genetic diseases; 11. Pregnant women; 12. Other reasons were not considered appropriate for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| chemotherapy response;outcome; | — |
Countries
China
Contacts
Public ContactRonghua Liu
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,
Outcome results
None listed