septic shock
Conditions
Interventions
Case series:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: age=18 ; patients wIth sepsis, according to sepsis-3 standard.
Exclusion criteria
Exclusion criteria: Severe arrhythmia (such as persistent or permanent atrial fibrillation); Moderate to severe valvular disease and after valve replacement; Other types of shock, such as hemorrhagic shock, obstructive shock, cardiogenic shock, and neurogenic shock; Patients transferred to ICU with sepsis diagnosed for more than 24 hours; length of ICU stay < 72 hours; Septic shock occurs within 24 hours after diagnosis of sepsis; the pregnant woman.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| left ventricular outflow tract velocity time integral (LVOT VTI);left ventricular ejection fractions (LVEF);snuffbox resistive index (SBRI);tricuspid annular plane systolic excursion (TAPSE);diastolic flow spectrum of mitral value (E/A);28-day mortality;soluble thrombomodulin (sTM);platelet counts;von willebrand factor (vwf);proealeitonin (PCT);Interleukin 6 (IL-6);peak systolic velocity measured at the mitral annulus (Sa)); | — |
Secondary
| Measure | Time frame |
|---|---|
| length of hospital stay;length of ICU stay; | — |
Countries
China
Contacts
Public Contactwanhong yin
West China Hospital of Sichuan University
Outcome results
None listed