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A study of cortico-cortical paired associative stimulation based on multisensory integration on brain network connectivity in stroke patients

A study of cortico-cortical paired associative stimulation based on multisensory integration on brain network connectivity in stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067422
Enrollment
Unknown
Registered
2023-01-06
Start date
2023-02-02
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

control group:sham stimulation
low-frequency group:low-frequency ccPAS treatment
high-frequency group:high-frequency ccPAS treatment

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Stroke (Infarction/Ischemia)40 2) Age = 40 years and = 70 years, regardless of sex41 3) Time of onset = three months and =1 year 4) right-handedness 5) normal cognitive function (MMSE above the threshold corresponding to different cultural levels) 6) Informed consent

Exclusion criteria

Exclusion criteria: 1) Contraindicated implants for MRI and TMS in vitro and in vivo 2) History of epilepsy, psychiatric disorders, or other serious cognitive or emotional disorders 3) History of medications that affect the central nervous system 4) Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer assessment scale-Upper Extremity;

Secondary

MeasureTime frame
Brunnstrom level;manual muscle test;Modified Ashworth test;range of motion;Minimum Mental State Examination;NIH Stroke Scale;Barthel index;Action Research Arm Test;The line bisection test;Modified Taylor Complex Figure;motor evoked potential;resting motor threshold;Amplitude of Low Frequency Fluctuation;Regional Homogeneity;

Countries

China

Contacts

Public ContactXuyun Hua

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

swrhxy@126.com+86 18916120869

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026