laparoscopic liver resection
Conditions
Interventions
Group B:Ulinastatin
Group C:Dexmedetomidine and Ulinastatin
Group D:0.9% Saline(placebo)
Sponsors
The First Affiliated Hospital,The Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1)Patients proposed to undergo laparoscopic liver resection (intraoperative hepatic blood flow block is required); 2)ASA grade I-III; 3)Child-Pugh score: Grade Child A or Grade Child B; 4)Voluntarily signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1)Age is <18 years old; 2)Child-Pugh score: Grade Child C; 3)Severe organ dysfunction such as the heart, lung, kidney, brain and other major organs; 4)Patients with liver trauma, living donor of liver transplantation, and a history of liver surgery or radiofrequency ablation; 5)Patients with II block or above or 2 or more bundle branch block; 6)Patients with pregnancy, drug addiction, and mental illness; 7)Patients allergied to any study drug; 8)Patients participating in other clinical trial studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT; | — |
Secondary
| Measure | Time frame |
|---|---|
| AST;TBIL;DBILI;IBILI;ALP;GGP;ALB;Lac;Time of hospital stay;complications(CDC-CCI);IL-6;CRP; | — |
Countries
China
Contacts
Public Contactzhu zhenghua
The First Affiliated Hospital,The Air Force Medical University
Outcome results
None listed