aortic aneurysm
Conditions
Interventions
Group 1:Anesthesia induction maintenance with propofol in patients undergoing endovascular aortic aneurysm repair
Group 2:Remazolam is induced at 6 mg/kg/h
Group 3:Remazolam is induced at 12 mg/kg/h
Sponsors
The First Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, gender is not limited; 2. Patients who plan to undergo elective endovascular repair of aortic aneurysm under general anesthesia; 3. ASA score III to IV; 4. Ability to comply with the research protocol; 5. Volunteer to participate in the research and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Emergency surgery patients; 2. Patients with difficult airway and acute upper respiratory infection; 3. Patients who cannot cooperate with the research for any reason such as language barriers and mental illnesses; 4. Patients with a history of allergy to diazepines or propofol; 5. Those who are participating in other clinical trials; 6. The researchers think other reasons are not suitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative extubation time;Genomic and metabonomic results of remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological function of patients after operation;Postoperative cardiovascular function;Respiratory function of patients after operation;Postoperative liver and kidney function;Stress and inflammatory reaction of patients after operation; | — |
Countries
China
Contacts
Public ContactWang Zhongxing
The First Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed