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Efficacy and safety of cycpofol combined with remifentanil in super-elderly patients undergoing orthopedic surgery: a prospective, randomized, double-blind, non-inferiority trial

Efficacy and safety of cycpofol combined with remifentanil in super-elderly patients undergoing orthopedic surgery: a prospective, randomized, double-blind, non-inferiority trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067390
Enrollment
Unknown
Registered
2023-01-06
Start date
2023-01-16
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative related diseases

Interventions

Group 2:Propofol

Sponsors

The 980th Hospital Of Joint Logistics Support Force
Lead Sponsor

Eligibility

Sex/Gender
All
Age
80 Years to 100 Years

Inclusion criteria

Inclusion criteria: The patients who underwent general anesthesia, ASA grade I-III, age > 80 years old, BMI < 30 kg/m2, liver and kidney function were normal.

Exclusion criteria

Exclusion criteria: 1. Long-term recipients of bronchiectasis and hormone therapy; 2. Long-term use of sedative, analgesic, antipsychotic and other drugs; 3. Combined with hypofunction or insufficiency of the adrenal cortex; 4. Patients with severe diabetes, hypertension, and renal insufficiency; 5. History of anesthesia drug allergy and contraindications; 6. People with cognitive impairment; 7. Family members or patients themselves refuse.

Design outcomes

Primary

MeasureTime frame
success rate of induction in general anesthesia;Postoperative cognitive function evaluation;

Secondary

MeasureTime frame
The maximum decrease in systolic blood pressure;time of successful induction of general anesthesia;The lowest BIS;Heart Rate;blood presure;Arterial blood gas analysis;

Countries

China

Contacts

Public ContactWu Yu

The 980th Hospital Of Joint Logistics Support Force

vwuyuv@163.com+86 186 3348 7638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026