chemotherapy-induced alopecia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Gynecological malignant tumors diagnosed by clinicopathology, including ovarian cancer, endometrial cancer, and cervical cancer; 2. Receive postoperative adjuvant chemotherapy or palliative chemotherapy for the first time; 3. Completed all TP (paclitaxel + cisplatin) or TC (paclitaxel + carboplatin) chemotherapy courses (4-8 courses); 4. According to Dean's Hair Loss Scale, subjectively evaluate the degree of hair loss >= 2 grades; 5. No medical history related to obvious hair loss; 6. The general condition is good, and the Karnofsky score is greater than or equal to 60 points; 7. The expected survival period is more than 3 months; 8. Female patients aged between 18 and 70 years; 9. Patients who agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who have suffered from hair loss diseases in the past; or are now accompanied by related diseases such as hair loss and alopecia areata, making it difficult to determine the curative effect; 2. Patients with severe organ dysfunction, such as heart, kidney and liver failure; 3. Coma, confusion, restlessness, abnormal movement, dementia, mental retardation, no independent judgment and extreme weakness; 4. Patients who have brain metastases during the treatment and need head radiotherapy; 5. Obvious blood coagulation dysfunction and skin infection and other diseases, affecting acupuncture treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grading of toxic effects on the severity of hair loss in World Health Organisation (WHO)Handbook for reporting results of cancer treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hair growth rate;Condition of hair growth ;Karnofsky Performance Status (KPS) Scale;Chemotherapy-induced Alopecia Distress Scale (CADS);quality of life index; | — |
Countries
China
Contacts
Guangdong Hospital of Traditional Chinese Medicine University City Hospital