The role and mechanism of LINC02528/IFI6 signal axis regulation network in the process of tuberculosis immune escape

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300067385

Enrollment

Unknown

Registered

2023-01-06

Start date

2023-01-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary tuberculosis

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with latent tuberculosis were positive by interferon gamma release test or tuberculin skin test, and had no clinical symptoms such as cough, expectoration and fever. The possibility of active tuberculosis was excluded by chest X-ray. After 2 years of follow-up, the patient was bacteriologically positive, including sputum smear, sputum culture, or bacteriologically negative, but clinically highly suspected of tuberculosis (clinically suspected symptoms, chest radiographs showed typical tuberculosis imaging characteristics), after anti-tuberculosis treatment imaging improved significantly, that is, the development of active tuberculosis.

Exclusion criteria

Exclusion criteria: Rule out diabetes mellitus, HIV, hepatitis b and serious cardiovascular, liver, kidney, hematopoietic system disease.

Design outcomes

Primary

Measure	Time frame
acteriological examination results;The results of the chest radiograph;clinical symptoms;	—

Countries

China

Contacts

Public ContactXu Yuzhong

Shenzhen Baoan District People's Hospital, the Second Affiliated Hospital of Shenzhen University

254501651@qq.com+86 134 1847 3391

Outcome results