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A study for genetic and immunological bases related to inborn errors of immunity underlying critical COVID-19 infection in children

A study for genetic and immunological bases related to inborn errors of immunity underlying critical COVID-19 infection in children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300067344
Enrollment
Unknown
Registered
2023-01-04
Start date
2023-01-04
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID19 infection

Interventions

None listed

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. The child has clear evidence of new coronavirus infection, and the basis for pathogen detection specimens; 2. Severe pneumonia/respiratory failure, necrotizing encephalitis, septic shock.

Exclusion criteria

Exclusion criteria: 1. Respiratory failure caused by laryngeal obstruction; 2. Ordinary febrile convulsions; 3. Serious basic diseases: diabetes, HIV, rheumatic diseases, blood system diseases, congenital heart disease, etc.; 4. Diagnose and clarify various genetic diseases; 5. Use of immunosuppressants: hormones, cyclosporine, mycophenolate mofetil, tacrolimus, azathioprine, cyclophosphamide, chemotherapy drugs, etc.

Design outcomes

Primary

MeasureTime frame
whole exome sequencing;—

Countries

China

Contacts

Public ContactYunfei An

Children's Hospital of Chongqing Medical University

1437535683@qq.com+86 138 9618 7845

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026