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Mechanism of transcranial magnetic stimulation to ventral precentral gyrus in improving post-stroke aphasia

Mechanism of transcranial magnetic stimulation to ventral precentral gyrus in improving post-stroke aphasia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067343
Enrollment
Unknown
Registered
2023-01-04
Start date
2023-01-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke aphasia

Interventions

Group 1:transcranial magnetic stimulation (vPCG)
Group 2:transcranial magnetic stimulation (IFG)
Group 3:transcranial magnetic stimulation (Sham)

Sponsors

Huashan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Stroke patients who meet the diagnostic criteria of Key Points for Diagnosis of Major Cerebrovascular Diseases in China 2019; 2. Age 35~70 years old; 3. Disease duration > 3 months; 4. Edinburgh Handedness Scale proves right handedness; 5. Mother tongue is Chinese; 6. For the first time and unilateral disease, confirmed by 2 rehabilitation medicine doctors with clinical experience, brain CT or MRI shows that the lesion is located in the left cerebral hemisphere; 7. The aphasia quotient is lower than 93.8 after evaluation by the Western Aphasia Complete Test (Chinese version); 8. The patient or authorized client signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Language impairment caused by post-stroke cognitive impairment; 2. People with other nervous system or mental diseases; 3. Have a history of epileptic seizures; 4. Have a history of pacemaker installation; 5. Those with metal foreign bodies or skull defects on the head; 6. People with claustrophobia; 7. Pregnant women; 8. Years of education < 3 years; 9. Others who cannot complete the assessment and treatment tasks required by the project.

Design outcomes

Primary

MeasureTime frame
The Main Concept Analysis, MCA;

Secondary

MeasureTime frame
Western Aphasia Battery, WAB;Boston naming test, BNT;Functional magnetic resonance imaging;Diffusion tensor imaging;

Countries

China

Contacts

Public ContactHu Ruiping

Huashan Hospital Affiliated to Fudan University

rphu79@163.com+86 15102161500

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026