Infertility
Conditions
Interventions
Experimental group:Administer gene recombinant follicle-stimulating hormone (r-FSH) 150-225u + gene recombinant luteinizing hormone (r-LH) 75u, inject once a day, for 5 consecutive days, the sixth day
Control group:From the start date, r-FSH (150-225u) was injected once a day for 5 consecutive days, and 75u r-LH was added on the 6th day according to the current clinical routine until the night acup
Sponsors
Reproductive Medical Center of Ruijin Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. The age of the woman is 20-40 years old, and the menstrual cycle is normal; 2. Both husband and wife have normal chromosomes; 3. Without adenomyosis and endometriosis; 4. No intramural fibroids > 4 cm, intrauterine adhesions or untreated endometrial polyps.
Exclusion criteria
Exclusion criteria: 1. The number of previous transplant failures = 3 times, or a history of recurrent miscarriage; 2. Have used oral contraceptives or estrogen and other drugs that may affect sex hormone levels within 3 months; 3. Patients with a history of radiotherapy and chemotherapy; 4. PCSO patients; 5. Patients undergoing PGT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| good-quality cleavage embryos; | — |
Secondary
| Measure | Time frame |
|---|---|
| follicle export rate;MII oocyte rate;fertility rate;available embryo rate;good embryo rate;Clinical pregnancy rate;Pregnancy loss rate; | — |
Countries
China
Contacts
Public ContactBufang Xu
Reproductive Medical Center of Ruijin Hospital, Shanghai Jiao Tong University
Outcome results
None listed