Observation on the Application of Different Degrees of Neuromuscular Block Combined with Laryngeal Mask General Anesthesia in Short Urological Surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300067327

Enrollment

Unknown

Registered

2023-01-04

Start date

2023-01-08

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:Induced by 1ED95 rocuronium

Group 2:Induced by 2ED95 rocuronium

Group 3:Induced by 3ED95 rocuronium

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who undergo elective urological surgery; 2. American Society of Anesthesiologists (ASA) grading I-III, age >= 18 years old, gender is not limited; 3. Estimated operation time < 90 minutes; 4. Voluntary subjects signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe liver and kidney insufficiency; 2. Predict respiratory difficulties; 3. Use of preoperative drugs that interact with non-depolarizing NMBAs (such as aminoglycosides, polymyxins, steroids, phenytoin, nerve inhibitors, carbamazepine); 4. Hypersensitivity to the drugs in the study; 5. Combined with neurological or psychiatric diseases.

Design outcomes

Primary

Measure	Time frame
The time of TOF recovery to 25%, 70%, and 90%;tidal volume;airway pressure;Oxygen saturation;The time of man-machine confrontation;The time to return to spontaneous breathing;Rating of laryngeal mask placement conditions;	—

Countries

China

Contacts

Public ContactShen Qiying

The First Affiliated Hospital of Anhui Medical University

shenqiying-yy@163.com+86 13956029032

Outcome results