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EC90 of Alfentanil combined with 0.075% ropivacaine for epidural labor analgesia: a single-center, prospective, double-blind sequential allocation biased-coin design

EC90 of Alfentanil combined with 0.075% ropivacaine for epidural labor analgesia: a single-center, prospective, double-blind sequential allocation biased-coin design

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067317
Enrollment
Unknown
Registered
2023-01-04
Start date
2023-01-05
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidural labor analgesia

Interventions

Group 1:Alfentanil is used for epidural labor analgesia

Sponsors

General Hospital of the Northern Theater Command of the Chinese People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Full-term (37-42 weeks), single pregnancy, primiparous women, all women and their families agree to labor analgesia and sign informed consent; 2. Aged 20-35 years old, American Society of Anesthesiologists (ASA) grade II, height 150-170 cm, body mass index BMI < 35 kg/m2; 3. No contraindications to spinal anesthesia, such as coagulation dysfunction, infection or injury at the puncture site, uncorrected maternal hypovolemia or hypotension, increased intracranial pressure, severe spinal deformity, etc.; 4. The dilation of the cervix is ??2~3 cm, the obstetrician and midwife have evaluated regular uterine contractions and meet the conditions for normal delivery; 5. No gestational diabetes, preeclampsia or eclampsia, placenta previa, no serious heart, brain, liver, kidney and other diseases, no complications such as intrauterine growth retardation or congenital abnormalities.

Exclusion criteria

Exclusion criteria: 1. The puerpera cannot cooperate with spinal canal puncture; 2. Unable to cooperate with visual analogue scale (VAS) score and VAS score before analgesia = 5 cm); 7. Use opioid analgesia before epidural analgesia.

Design outcomes

Primary

MeasureTime frame
Visual analog (VAS) scores at 30 minutes after epidural analgesia;

Countries

China

Contacts

Public ContactCao Huijuan

General Hospital of the Northern Theater Command of the Chinese People's Liberation Army

caohuijuan1212@sina.com+86 13309880882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026