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Efficacy of omega-3 fatty acid adjunctive with sertraline in nonsuicidal self-injury behavior of child and adolescents with major depressive disorder

Efficacy of omega-3 fatty acid adjunctive with sertraline in nonsuicidal self-injury behavior of child and adolescents with major depressive disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300067298
Enrollment
Unknown
Registered
2023-01-03
Start date
2023-01-13
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

Experimental group :Sertraline + fish oil capsules
Control group :Sertraline

Sponsors

Chaohu Hospital Affiliated to Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 12 and 18 years, no gender limit; 2. Meet the diagnostic criteria for depressive disorders in DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th Edition); 3. Hamilton Depression Scale (HAMD-24) score above 20 points; 4. Primary school education or above; 5. Understand the study content, be willing to participate in the study, and sign written informed consent by the patient or the patient's family.

Exclusion criteria

Exclusion criteria: 1. Have bad habits (including smoking, drinking, etc.); 2. Unstable diet, overeating and other conditions; 3. Oral ulcer, periodontitis, gingival bleeding and other oral diseases; 4. Recently taking antibiotics, hormones and other drugs.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale;

Secondary

MeasureTime frame
Cognitive Function Rating Scale;

Countries

China

Contacts

Public ContactZhang Kai

Chaohu Hospital Affiliated to Anhui Medical University

Zhangkai@ahmu.edu.cn+86 18921104636

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026