insomnia
Conditions
Interventions
Treatment group:Acupuncture and moxibustion treatment
Control group:False needle therapy
Healthy people group:None
Sponsors
Shandong Provincial Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patient: (1) Meet the diagnostic criteria for insomnia in the Diagnostic and Statistical Manual of Mental Disorders (5th Edition) of the American Psychiatric Association; (2) No gender limit, aged between 18 and 70 years; (3) PSQI score >=7 points; (4) Not taking any neuropsychiatric drugs or receiving acupuncture treatment in the past 1 month; (5) VAS score >=5 points; (6) Know relevant matters, can cooperate with acupuncture treatment, voluntarily participate in this experiment and sign the informed consent; 2. Healthy people: (1) Good physical condition, good sleep condition, no organic or serious functional disease, no history of mental illness. (2) No gender limit, aged between 18 and 70 years; (3) No acupuncture treatment in the past 1 month; (4) Volunteer to participate in this experiment and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating patients; 2. Patients with severe mental illness; 3. Prone to co-infection, or have a history of spontaneous bleeding tendency; 4. Patients with history of serious primary diseases of cardiovascular, cerebrovascular, liver, kidney and hematopoietic systems; 5. Patients with alcohol dependence; 6. Patients with severe gastrointestinal diseases; 7. Take antibiotics, glucocorticoids, immunosuppressants, or probiotics and other microecological preparations within 1 month.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index;Self-rating Anxiety Scale;Self-rating Depression Scale;Visual Analogue Scale score for insomnia;Intestinal flora; | — |
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index;Serum GABA content and protein expression level;Serum GABA ARa1 content and protein expression level;Serum GABA AR?2 content and protein expression level; | — |
Countries
China
Contacts
Public ContactZhou E
Shandong Provincial Third Hospital
Outcome results
None listed