Type 1 diabetes
Conditions
Interventions
Group 1:insulin pump+dynamic blood glucose monitoring
Group 2:insulin pump+dynamic blood glucose monitoring+closed loop treatment for 3 months
Group 3:insulin pump+dynamic blood glucose monitoring+cosed loop treatment for 6 months
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnosis of diabetes: In 2019, WHO issued the new classification criteria, and meeting one of the following 4 criteria can diagnose diabetes: (1) Fasting blood glucose >=7.0 mmol/L; (2) Blood glucose >=11.1 mmol/L 2 h after oral glucose tolerance load [glucose 1.75 g/kg (body weight), maximum glucose 75 g]; (3) HbA1c>=6.5% (HbA1c determination method requires certification by the United States Glycosylated Hemoglobin Standardization Program); (4) Random blood glucose >=11.1 mmol/L with diabetes symptoms and signs; For those who meet the above criteria but are asymptomatic, repeat testing on the following 1 day is recommended to confirm the diagnosis. 2. Patients with T1DM who have been diagnosed for at least 6 months. 3. Use insulin pump for >=3 months. 4. Live with an adult willing to care for the subject during the study period, and the guardian will sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe acute or chronic diabetic complications, including microvascular or macrovascular complications; 2. Severe hypoglycemia occurred frequently in the recent 3 months; 3. Recurrent diabetic ketoacidosis in the recent 3 months (>2 times); 4. People who used closed loop before participating in the experiment; 5. Physical or psychological conditions deemed unsuitable for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of time within the target range; | — |
Countries
China
Contacts
Public ContactSun Yan
Shandong Provincial Hospital
Outcome results
None listed