acute kidney injury (AKI)
Conditions
Interventions
experimental group:On the basis of standard treatment, add Shenfu injection 100ml+0.9% NS 250ml intravenous drip for 3 days
control group:On the basis of the standard treatment, 350ml of the same amount of normal saline was added for intravenous drip for 3 days
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of sepsis 3.0; 2. Aged >= 18 years; 3. Expected ICU stay >= 72 hours; 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic renal insufficiency, anuria or oliguria requiring hemodialysis. 2. Patients who could not obtain basic renal function parameters. 3. Patients with a known history of allergy to sulfur hexafluoride or other components. 4. Patients with recent acute coronary syndrome or clinically unstable ischemic heart disease, including progressive or progressive myocardial infarction; Typical angina pectoris during the past 7 days of silence; Cardiac symptoms have worsened significantly in the past 7 days; Recent coronary interventional surgery or other factors suggestive of clinical instability (e.g. recent deterioration in ECG, laboratory or clinical findings); Acute heart failure, grade III/IV heart failure and severe arrhythmia. 5. Adult patients with respiratory distress syndrome with right-to-left shunt, severe pulmonary hypertension, uncontrolled hypertension, and no artificial airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| creatinine;urea nitrogen;contrast-enhanced ultrasound measurement;urine output; | — |
Countries
China
Contacts
Public ContactPu Hong
West China Hospital of Sichuan University
Outcome results
None listed