liver cancer
Conditions
Interventions
laparoscopy group:Laparoscopic resection
laparotomy group :Laparotomy resection
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Preoperative diagnosis of NAFLD-HCC: The diagnostic criteria for HCC were in accordance with the clinical diagnostic criteria for HCC established by the American Association for the Study of Liver Diseases (AASLD). NAFLD: 1. Exclude all chronic liver diseases that may cause liver cancer (such as chronic viral hepatitis B, chronic viral hepatitis C, alcoholic liver disease, autoimmune liver disease, hemochromatosis, primary sclerosing cholangitis, etc.). 2. Previous or current abdominal color ultrasound examination indicated the presence of fatty liver, alcohol intake =25 kg/m^2, waist circumference: male >=94cm, female >=88cm; 110 mg/dL fasting blood glucose or a diagnosis of type 2 diabetes; Lipid metabolism disorders: triglycerides > 1.7 mmol/L (150 mg/dL), HDL =130/85 mmHg or undergoing antihypertensive treatment.
Exclusion criteria
Exclusion criteria: 1. Liver resection combined with other organ operations except gallbladder; 2. Preoperative impact examination indicated that the tumor obviously invaded the portal vein or hepatic artery; 3. Any previous tumor therapy, such as PVE, TACE, targeting, immunology or systemic combination therapy; 4. Liver function Child-Pugh grade C; 5. Extrahepatic metastasis or invasion of other organs was found during the operation; 6. Patients who have not signed the informed consent of the subjects in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| operative combidity; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-year overall survial;5-year tumor-free survival rate;intraoperative related events;incidence of incisional hernia;health quality of life assessment; | — |
Countries
China
Contacts
Public ContactJiang Li
West China Hospital of Sichuan University
Outcome results
None listed