haematologic malignancies
Conditions
Interventions
intervention group:Conventional transplantation treatment + psychological intervention
control group:Conventional transplantation treatment
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with hematological tumors and proposed to undergo hematopoietic stem cell transplantation; 2. Aged 16 years and above; 3. Hematopoietic stem cell transplantation for the first time; 4. Normal renal function (defined as creatinine clearance >=30ml/min and creatinine less than 160µmol/L); Normal liver function (defined as ALT and AST=50% predictive value of FEV1, FVC, DLCO) normal cardiac function (left ventricular ejection fraction >=40%, asymptomatic arrhythmia); 5. Eastern Cooperative Oncology Group (ECOG) daily physical fitness score 0-1; 6. Neutrophil absolute value >=1.5x10^9/L, platelet >= 90x10^9/L, hemoglobin >= 90g/L; 7. Expected survival time >=3 months; 8. Able to understand Chinese correctly and complete the questionnaire independently; 9. Volunteer to participate in the study and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with serious physical disease or cognitive impairment cannot participate in this study; 2. Severe depressive symptoms and suicidal thoughts; 3. Received psychotherapy within a year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Assessment of Cancer Therapy-Bone Marrow Transplant, FACT-BMT; | — |
Secondary
| Measure | Time frame |
|---|---|
| FACT-Fatigue Subscale, FACT-F;The Revised Edmonton Symptom Assessment Scale, ESAS;Patients' Health Questionnaire Depression Scale 9-item, PHQ-9;The Generalized Anxiety Disorder 7-item, GAD-7;Pittsburgh Sleep Quality Index, PSQI;The Post-Traumatic Stress Disorder Checklist-Civilian Version 5-item, PCL-5;Connor-Davidson Resilience Scale, CD-RISC-10;Social Support Rating Scale, SSRS; | — |
Countries
China
Contacts
Public ContactWang Yu
West China Hospital, Sichuan University
Outcome results
None listed