Application of autologous blood separation technique in liver resection

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200067232

Enrollment

Unknown

Registered

2022-12-30

Start date

2023-01-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic space occupation

Interventions

Autoblood separation technology group:Use autologous blood separation technique

Control group:Allogeneic blood products were transfused when neededd

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Selective partial hepatectomy is proposed; 2. Aged >=18 years; 3. ASA grade I-II; 4. Body mass index (BMI) 18-30 kg/m^2; 5. Child-Pugh for liver function was grade A-B, with liver resection >=3 segments or A single lump diameter >=5cm.

Exclusion criteria

Exclusion criteria: 1. Obvious abnormal coagulation function and diseases related to the coagulation system existed before surgery; 2. Preoperative hemoglobin < 110g/L, hematocrit < 33%, platelet < 100×10^9/L; 3. Take anticoagulant drugs or antiplatelet drugs within one month; 4. Portal/inferior vena cava thrombosis, cancer thrombus; 5. The puncture site has inflammation, infection, abnormal anatomy of the puncture vessel, thrombosis and other conditions that are not suitable for puncture; 6. The patient or family member refuses.

Design outcomes

Primary

Measure	Time frame
Transfusion volume of allogeneic blood products;Thrombologram;	—

Secondary

Measure	Time frame
Coagulation function;Blood routine;Liver and kidney function;	—

Countries

China

Contacts

Public ContactJiang Xiaojuan

West China Hospital, Sichuan University

jiangxiaojuan@scu.edu.cn+86 18328304306

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026