Premature ovarian insufficiency
Conditions
Interventions
Conventional treatment group:Conventional treatment to POI
PRP treatment group:PRP intraovarian injection
Sponsors
Women's Hospital School of Zhejiang University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years, < 40 years, ordinary community female; 2. The patient voluntarily accepted clinical observation and signed informed consent; 3. The patient had no previous diagnosis of POI or had to stop POI-related therapy for more than 3 months.
Exclusion criteria
Exclusion criteria: 1. Previous history of bilateral ovariectomy; 2. There are contraindications in fingertip blood collection, such as local skin infection and coagulation dysfunction; 3. There are contraindications of POI treatment; 4. Patients judged by the researchers to be unfit to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-Müllerian hormone;Follicle-stimulating hormone;Estrogen;Antral follicle count;Pregancy rate;Live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Abortion rate;Blood routine;Hepatorenal function;Egg retrival number;Zygote number;Success rate of embryo transfer; | — |
Countries
China
Contacts
Public ContactWu Ruijin
Women's Hospital School of Zhejiang University
Outcome results
None listed