Cough
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (i) age =65 years; (ii) The American Society of Anesthesiologists (ASA) Physical Status Classification I, II and III; (iii) scheduled to undergo elective surgery under general anaesthesia requiring tracheal intubation; (iv)patients can tolerate operation and are no allergic reaction to anesthetics; and (v) signed informed consent.
Exclusion criteria
Exclusion criteria: (i) patients underwent neurosurgery surgery, cardiovascular surgery or nighttime surgery; (ii) combination of other vital organ dysfunctions: including severe liver and kidney dysfunction; organic brain diseases, specifically aneurysmal vascular disease or arteriovenous malformation and cerebral hemorrhage; severe hypertension, coronary heart disease, cardiac insufficiency (NYHA >= grade III); abnormal coagulation function; severe respiratory system diseases; (iii) patients with preoperative behavior disorder or combined mental illness who have used psychotropic drugs; (iv) patients with the long-term use of sedative drugs or glucocorticoid; (v) those with a history of alcohol or drug dependence; and (vi)patients deemed unsuitable for inclusion by other investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough before extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| time from the end of surgery to spontaneous breathing recovery;time from the end of surgery to eye opening;time from cessation of sedation administration to extubation;time from the end of surgery to orientation recovery;PACU length-of-stay; | — |
Countries
China
Contacts
The First Affiliated Hospital of Sun Yat-sen University