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Subserratus anterior plane block compared with paravertebral block in patients undergoing laparoscopic radical nephrectomy with opiod-reduced multimodal analgesia: A prospective randomized controlled non-inferiority clinical trial

Subserratus anterior plane block compared with paravertebral block in patients undergoing laparoscopic radical nephrectomy with opiod-reduced multimodal analgesia: A prospective randomized controlled non-inferiority clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200067131
Enrollment
Unknown
Registered
2022-12-27
Start date
2024-05-17
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal tumor

Interventions

Group S:subserratus plane block

Sponsors

Quanzhou First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Laparoscopic nephrectomy; 2. Aged 18 years and above; 3. ASA grade I-III; 4. BMI 18-30 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Coagulation disorder; 3. Mental illness; 4. Long term use of analgesics; 5. Previous abdominal surgery history; 6. Those who switched to open surgery; 7. Thoracic paraspinal block and low anterior serratus block were contraindicated; 8. Complicated with serious medical diseases: heart, lung, liver and kidney insufficiency; 9. Spinal deformity and Invasive advanced renal cell carcinoma.

Design outcomes

Primary

MeasureTime frame
Total dose of butorphanol consumed within 24 hours after operation;

Secondary

MeasureTime frame
Visual Analogue Scale (VAS) score;heart rate;mean arterial pressure;Time consumption of nerve block puncture;Interleukin-6;C-reactive protein;White blood cell count;Intraoperative fentanil dosage;Intraoperative use of vasoactive drugs;Postoperative rehabilitation index;Time point of the first PCA press;Butorphanol consumption 48 hours postoperatively;Duration of hospitalization;time to return to anal defecation;Incidence of chronic pain 6 months postoperatively;

Countries

China

Contacts

Public ContactJianghuai Lin

Quanzhou First Hospital

curry26283599@163.com+86 130 5552 4595

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026