High altitude sickness
Conditions
Interventions
Plain environment group:NA
Sponsors
Army Medical Center (Daping Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-45, without any known infectious diseases; Not been to endemic diarrhea areas in the last 6 months; Have lived in plain/plateau environment in the past 6 months. 2) In a healthy condition, normal weight, body mass index (BMI) 18.5-24.9 kg/m2; 3) No complications of heart, brain, lung, liver, kidney and other serious diseases, no mental disorders, with normal communication skills 4) With no alcoholism 5) No history of ulcerative colitis or other gastrointestinal diseases 6) Not taking any antacids, gastrointestinal motility drugs, antibiotics and live intestinal microflora preparations (such as yogurt) within the past 4 weeks 7) Signed the informed consent form and agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1) History of autoimmune disease and digestive system surgery; 2) Atopic diseases, such as eczema, asthma, and gastrointestinal eosinophil-related diseases; 3) Took antibiotics, drugs that cause intestinal microecological disorders, and any immunosuppressive agents within the past 3 months. 4) Pregnant and lactating women; 5) Complicated with hypertension, diabetes, heart disease, stroke or severe chronic diseases (infectious, hereditary, metabolic, endocrine diseases); 6) Subjects who are unable to cooperate with the study or who are considered by the investigator to be unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in metabolic compounds;Gastrointestinal disorders;Depression and anxiety;Fatigue;Sleep condition;Health condition; | — |
Countries
China
Contacts
Public ContactWei Yanling
Army Medical Center (Daping Hospital)
Outcome results
None listed