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Clinical study on Qilinghuaxian Formula in treating hepatitis B virus-related liver cirrhosis and development of hospital preparations

integrated Chinese and Western medicines

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200067068
Enrollment
Unknown
Registered
2022-12-26
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatitis B virus-related liver cirrhosis

Interventions

NAs+"Qilinghuaxian Formula" Group:NAs+"Qilinghuaxian Qilinghuaxian Formula" combined treatment
NAs treatment Group:NAs treatment
NAs+Fuzhenghuayu Capsule Group:NAs+Fuzhenghuayu Capsule combined treatment

Sponsors

Ningbo No. 2 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.All patients with HBV related compensated cirrhosis who received NAs antiviral treatment were included in this study. The untreated patients were active liver cirrhosis with positive HBV DNA (= 30 IU/ml), and the treated patients were still liver cirrhosis with negative HBV DNA (<30 IU/ml) who had received anti viral therapy with NAs. 2.Subjects aged 18-70 years, regardless of gender. 3.Volunteer to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women. 2.Inability to cooperate in completing research or poor compliance. 3.Co-infected with HAV, HCV, HDV, HEV. 4.Complicated with severe circulatory, nervous and immune system diseases. 5.Autoimmune, alcoholic, drug - induced liver disease and other liver diseases.

Design outcomes

Primary

MeasureTime frame
Serological markers of hepatic fibrosis;Abdominal ultrasound examination;Liver stiffness;Blood routine examination;Blood biochemical indexes;Transforming growth factor- ß 1;

Countries

China

Contacts

Public ContactAirong Hu

Ningbo No. 2 Hospital

huairong6666@126.com13968369377

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026