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The improvements of sodium alginate supplementation on non-alcoholic fatty liver disease and related mechanism

The improvements of sodium alginate supplementation on non-alcoholic fatty liver disease and related mechanism

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200067065
Enrollment
Unknown
Registered
2022-12-26
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nonalcoholic fatty liver disease

Interventions

Intervention group:5g/d protein powder + 5g/d Sodium Alginate
Control group:5g/d protein powder + 5g/d Inulin
Placebo group:5g/d protein powder + 5g/d Maltodextrin

Sponsors

College of Public Health, Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1 ) No drinking history or alcohol consumption 19U / L and male volunteers ALT > 30U / L ; 4 ) 35-75 years old ; 5 ) Willing to sign informed consent.

Exclusion criteria

Exclusion criteria: Those with the following items cannot be included in the group : 1 ) Familial hyperlipidemia or triglyceride concentration greater than 4.56mmol / L ; 2 ) Suffering from cardiovascular and cerebrovascular diseases, any form of kidney and malignant tumors and other diseases ; 3 ) Specific liver diseases such as viral hepatitis, drug-induced liver disease, hepatolenticular degeneration and autoimmune liver disease that can lead to fatty liver ; 4 ) pregnant or lactating women ; 5 ) Have taken prebiotics or probiotics within three months.

Design outcomes

Primary

MeasureTime frame
Anthropometric parameters;Blood biochemical index;Abdominal ultrasound;Metabolome;Intestinal flora;

Countries

China

Contacts

Public ContactXiaofei Guo

College of Public Health, Qingdao University

guoxf@qdu.edu.cn15990020643

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026