Postoperative acute pain and Depressed
Conditions
Interventions
Control goup:PCIA(Sufentanil 100ug+Palonosetron0.5mg+0.9% normal saline to 100ml)
Intervention group:PCIA((Esketamine 1mg ? kg-1+sufentanil 100ug+Palonosetron 0.5mg+normal saline to 100ml))
Sponsors
Fisrt Hospital of Putian, Putian,Fujian
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) The elective operation conforms to the indication of cesarean section; (2) No contraindication of spinal anesthesia. (3) American Association of Anesthesiologists (ASA) Grade I - II.
Exclusion criteria
Exclusion criteria: (1) Pathological obstetric diseases; (2) People with depression and other mental symptoms; (3) People with drug allergy; (4) History of alcohol or drug dependence for more than 6 months; (5) History of ketamine abuse or dependence; (6) Those with abnormal coagulation function, liver and kidney function, or hypertension or diabetes; (7) Poor compliance, midway spontaneous labor to cesarean section.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| free cortisol;atrial natriureticpeptide;epinephrine;Nepinephrine;Cognitive dysfunction;edinburgh postpartum depression scale; | — |
Countries
China
Contacts
Public ContactShurong Li
Fisrt Hospital of Putian, Putian,Fujian
Outcome results
None listed