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Effect of Esketamine on perioperative cognitive and depressive status in elderly patients undergoing abdominal surgery

Effect of Esketamine on perioperative cognitive and depressive status in elderly patients undergoing abdominal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200067050
Enrollment
Unknown
Registered
2022-12-26
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression and Cognitive dysfunction

Interventions

Esketamine:Esketamine 0.2 mg/kg
Control:Normal saline

Sponsors

Cangzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients undergoing abdominal surgery under selective general anesthesia (2) Aged = 60 (3) ASA II-III (4) Patients and their families are willing to accept the survey contents involved in this study

Exclusion criteria

Exclusion criteria: (1) Patients with mental illness or cognitive impairment (2) Patients who participated in other clinical studies within 3 months (3) Patients with systemic organ dysfunction (4) Patients unwilling or unable to participate in and complete the study

Design outcomes

Primary

MeasureTime frame
confusion assessment model for intensive care unit, CAM-ICU;Mini-mental State Examination,MMSE;Montgomery-Asberg Depression Rating Scale;Generalized Anxiety Disorder,GAD-7;—

Secondary

MeasureTime frame
C-reactive protein,CRP;15-item quality of recovery scale, QOR-15;Patient Health Questionnaire-9,PHQ-9;Perioperative complications;—

Countries

China

Contacts

Public ContactYan Li

Cangzhou Central Hospital

1306572670@qq.com18103375267

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026