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Exploring the effects of short peptides food for special medical purposes components on nutritional status and intestinal barrier function in critically ill patients

Exploring the effects of short peptides food for special medical purposes components on nutritional status and intestinal barrier function in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200067017
Enrollment
Unknown
Registered
2022-12-23
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Serious illness

Interventions

trial group:short peptide food for special medical purposes components + Short peptide type full nutrition preparation
control group:Short peptide type full nutrition preparation

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with a clear diagnosis of severe disease, including severe pancreatitis, sepsis, severe burns, trauma, and recovery from major surgery; 2. Aged 18-70 years; 3. NRS2002 >= 3 points; 4. Enteral nutrition support by tube feeding; 5. Signed informed consent form.

Exclusion criteria

Exclusion criteria: 1. Oral supplementation or total parenteral nutrition support; 2. Severe liver and kidney disease, malignancy, severe protein malnutrition (serum albumin < 20 g/L); 3. Women during pregnancy or lactation; 4. Fecal incontinence; 5. Ongoing participation in other clinical trials; 6. Other conditions that, in the opinion of the investigator, make the patient unsuitable for participation in this study.

Design outcomes

Primary

MeasureTime frame
Albumin;Hemoglobin;Prealbumin;Serum intestinal fatty acid binding protein;Diamine oxidase;

Secondary

MeasureTime frame
D Lactate level;Weight;Potassium;Glucose;Gut flora;

Countries

China

Contacts

Public ContactLiu Yuan

West China Hospital of Sichuan University

liuyuan_7502@163.com+86 189 8060 6459

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026