Hashimoto thyroiditis
Conditions
Interventions
Dietary fiber group:Dietary fiber
Comprehensive treatment group:the Combination of Cereal Dietary Fiber and "Xiaoying Tie"
control group:Lifestyle intervention
Sponsors
Shanghai Jing'an Zhabei Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Those who meet the above diagnostic criteria and whose serum TGAb and TPOAb indicators are within the measurable range have clinical hyperthyroidism and hypothyroidism, and thyroid function is normal; 2. The patient is conscious and willing to participate in the study and sign the informed consent form; 3. Aged > 18 years.
Exclusion criteria
Exclusion criteria: 1. Patients with goiter and compression of adjacent organs or patients with thyroid heart disease; 2. Thyroid enlargement with exophthalmos, TGAb (+), slightly increased TPOAb titer and other thyroid diseases diagnosed; 3. People with serious heart, liver, kidney and other organ complications and blood system diseases; 4. Pregnant or lactating women; 5. Patients with allergic constitution or known hypersensitivity to food and drugs used in the test; 6. Those with poor compliance, withdrawal and incomplete data, but those with adverse reactions were counted; 7. Gastrointestinal ulcer, erosive gastritis, atrophic gastritis, severe dysplasia of gastric mucosa, or suspected malignant disease are complicated; 8. Patients with gastroesophageal reflux disease or irritable bowel syndrome; 9. In the past 3 months, the following diseases received medical treatment: cholecystitis,gastrointestinal ulcer, urinary tract infection, acute pyelonephritis, cystitis; 10. Have undergone gastrointestinal surgery, such as appendectomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroglobulin antibody, TGAb;Diversity and composition of intestinal flora;Thyroid peroxidase antibody, TPOAb; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase;Creatinine;routine blood test;Free triiodothyronine, FT3;Free thyroxine, FT4;Thyroid stimulating hormone;Cytokine TNF- a;Cytokine IL-10;Cytokine IL-6;Cytokine INF-y;regulatory T cell, Treg; | — |
Countries
China
Contacts
Public ContactPan Jing, Zhang Meizhu
Shanghai Jing'an Zhabei Central Hospital; Shanghai Jing'an District Baoshan Road Neighborhood Community Health Service Center
Outcome results
None listed