STEMI
Conditions
Interventions
experimental group:rosuvastatin, 20mg/d
Control group:rosuvastatin, 10mg/d
Sponsors
QingPu Branch of Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
75 Years to 100 Years
Inclusion criteria
Inclusion criteria: ? The diagnosis was consistent with STEMI(Guidelines for the Diagnosis and Treatment of Acute ST-Segment Elevation Myocardial Infarction (2019)); ? Age =75 years old; ?The blood flow of target-vessel was restored to TIMI 3 after PPCI;
Exclusion criteria
Exclusion criteria: 1. Severe cardiac insufficiency (cardiac function grade ?-?), liver insufficiency (serum aminotransferase continuously increased more than 3 times the upper limit of normal) or renal insufficiency (eGFR<30 mL/min); ? Lipid-lowering and antioxidant drugs were used 2 weeks before hospitalization; (3) Patients who are allergic to rosuvastatin or have definite medical history and can not take rosuvastatin or have muscle soreness during taking rosuvastatin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood lipid; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum inflammatory biomarkers;Index of ventricular remodeling;Index of cardiac function; | — |
Countries
China
Contacts
Public ContactRongLuo
QingPu Branch of Zhongshan Hospital, Fudan University
Outcome results
None listed