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A retrospective study of tranexamic acid combined with different antibacterial drugs during total knee replacement affecting the incidence of DVT in the lower extremities after surgery

A retrospective study of tranexamic acid combined with different antibacterial drugs during total knee replacement affecting the incidence of DVT in the lower extremities after surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066954
Enrollment
Unknown
Registered
2022-12-22
Start date
2023-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

DVT

Interventions

TXA+Cefuroxi group:N/A
TXA+Cefazolin group:N/A

Sponsors

Shanghai Tenth People’s Hospital, Tongji University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 96 Years

Inclusion criteria

Inclusion criteria: Patients who received tranexamic acid + cefazolin, tranexamic acid + cefuroxime during the operation

Exclusion criteria

Exclusion criteria: a. Previous history of DVT/PTE; b. Intraoperative and postoperative blood transfusion; c. Diseases related to the blood system; d. Surgical operations within the last 3 months; e. female menstrual period or pregnancy, etc. f. History of malignant tumor.

Design outcomes

Primary

MeasureTime frame
D-dimer;CRP;Doppler ultrasound of the lower extremities;—

Secondary

MeasureTime frame
IL-6;WBC;—

Countries

CHINA

Contacts

Public Contactfanghuang

Shanghai Tenth People's Hospital

ranranwu1993@163.com15821690871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026