Heatstroke
Conditions
Interventions
Heatstroke group:None
Spesis group:None
CPB group:None
Healthy Control group:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. HS group: (1) age = 18 years; (2) History of exposure to extreme environmental heat OR vigorous muscle exertion; (3) Core body temperature >40? OR symptoms of central nervous system (CNS) dysfunction, such as coma, delirium and convulsions; (4) Agree to participate, and give signed written informed consents. 2.S group (1) Age = 18 years; (2) Suspected or known infection; (3) Sequential organ failure assessment (SOFA) score =2 points; (4) Agree to participate, and give signed written informed consents. 3.CPB group (1) Age = 18 years; (2) Underwent valve replacement surgery or coronary artery bypass surgery under cardiopulmonary bypass (3) Agree to participate, and give signed written informed consents. 4.HC group (1) Age = 18 years; (2) Body Mass Index (BMI): 18~24 (3) Provide health examination report within 6 months (4) Agree to participate, and give signed written informed consents.
Exclusion criteria
Exclusion criteria: (1) Pregnant woman; (2) Combined with immune system diseases, hematological diseases (3) Combined with malignant tumor,and receiving radiation, chemotherapy, or other treatments (3) History of organ transplantation OR bone marrow transplantation (4) Received immunotherapy within 6 months prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite index (the incidence of death, neurological dysfunction, heart failure, renal failure, or respiratory failure); | — |
Secondary
| Measure | Time frame |
|---|---|
| Composite index (the incidence of renal dysfunction, or gastrointestinal complications)); | — |
Countries
China
Contacts
Public ContactLei Du
West China Hospital, Sichuan University
Outcome results
None listed