Respiratory failure of premature infants
Conditions
Interventions
inhaled nitric oxide:N/A
Sponsors
Xiamen Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? The gestational age at birth was 22-37 weeks; ? Receive invasive or non-invasive respiratory support; ? Receive iNO treatment and maintain it for more than 3 hours.
Exclusion criteria
Exclusion criteria: ? Congenital malformation or genetic metabolic disease; ? Complex congenital heart disease (except atrial septal defect or ventricular septal defect) ? NO was applied after various surgical treatments in neonatal period;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| iNO usage rate;Treatment outcome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease spectrum of premature infants using iNO;Positive rate of iNO treatment;Direct causes of NO use in premature infants;Before and 3 ± 1h, 24 ± 6h, 48 ± 6h, 72 ± 6h after the treatment of iNO (recorded at 24h intervals until NO evacuation), blood gas indicators (pH, PaO2, PaCO2, SBE), SPO2 before and after the catheter and difference, oxygenation index (OI), P/F (PaO2/FiO2) values;Ventilator parameters (FiO2, MAP, Pose, RR) before and 3 ± 1h, 24 ± 6h, 48 ± 6h, 72 ± 6h after treatment with iNO (recorded at 24h intervals until NO evacuation);INO treatment start time (d+h), initial dose (ppm), maximum dose (ppm), maintenance time (d+h);Pulmonary artery pressure measured by cardiac ultrasound before iNO treatment or 24h, 48h and 72h after treatment;General situation;Maternal diseases;Auxiliary ventilation mode and time;medication;Monitoring of platelet count and coagulation function after iNO;Impact of complications;Hospitalization days; | — |
Countries
China
Contacts
Public ContactLin xinzhu
Xiamen Maternal and Child Health Care Hospital
Outcome results
None listed