Liver cirrhosis
Conditions
Interventions
Variable diameter stents surgery group:Variable diameter stents
Traditional constant diameter stents surgery group:Constant diameter stents
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 to 75 years; 2. Patients who are diagnosed according to clinical manifestations, laboratory and imaging examinations; 3. Patients with esophageal and gastric varices bleeding or refractory hydrothorax/ascites.
Exclusion criteria
Exclusion criteria: 1. Previous TIPS or surgical shunt; 2. Recurrent attacks of hepatic encephalopathy(more than 2 times); 3. Cavernous transformation of portal vein; 4. Child-Pugh score is greater than 11; 5. Dysfunction of organs including heart, lung, kidney and brain; 6. Liver cancer and other malignant tumors beyond Milan criteria; 7. From high altitude area (higher than 2500 meters above the sea level); 8. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decompensated liver cirrhosis events such as bleeding, ascites and hepatic encephalopathy;Blood biochemical indices;Adverse events such as liver failure, infections and death; | — |
Countries
China
Contacts
Public ContactHao Wu
West China Hospital, Sichuan University
Outcome results
None listed